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Insitute of Mathematical Science

Applied Mathematical Seminar 60: Modelling manifold-valued time series data from EEG studies of patients with epilepsy

Seminar| Institute of Mathematical Sciences

Time: Thursday, January 18th, 2024 , 16:30-17:30

Location🤸🏼:RS408, IMS
Speaker: Tao Ding,  Newcastle University, UK 

AbstractWe propose a model for time series taking values on a Riemannian manifold and fit it to time series of covariance matrices derived from EEG data for patients suffering from epilepsy. The aim of the study is two-fold: to develop a model with interpretable parameters for different possible modes of EEG dynamics, and to explore the extent to which modelling results are affected by the choice of manifold and its associated geometry. The model specifies a distribution for the tangent direction vector at any time point, combining an autoregressive term, a mean reverting term and a form of Gaussian noise. Parameter inference is carried out by maximum likelihood estimation, and we compare modelling result obtained using the standard Euclidean geometry on covariance matrices and the affine invariant geometry. Results distinguish between epileptic seizures and periods between seizures in patients: between seizures the dynamics have a strong mean reverting component and the autoregressive component is weaker, while during seizures the noise term has greater variance and the mean reverting effect is smaller. The results also capture differences between the seizures within each patient. The affine invariant geometry is advantageous and it provides a better fit to the data.


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